Simple Catalytic Mechanism for the Direct Coupling of α-Carbonyls with Functionalized Amines: A One-Step Synthesis of Plavix

Ryan W. Evans, Jason R. Zbieg, Shaolin Zhu, Wei Li, and David W. C. MacMillan

J. Am. Chem. Soc., 2013, 135 (43), pp 16074–16077

DOI: 10.1021/ja4096472