Communication Regio- and Enantioselective Synthesis of Pyrrolidines Bearing a Quaternary Center by Palladium-Catalyzed Asymmetric [3 + 2] Cycloaddition of Trimethylenemethanes

 

 

Barry M. Trost *, Tom M. Lam , and Melissa A. Herbage

J. Am. Chem. Soc., 2013, 135 (7), pp 2459–2461

DOI: 10.1021/ja312351s